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Authors Potretzke AM, Wong KS, Shi F, Christensen W, Downs TM, Abel EJ
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Journal Urol Ann Volume: 7 Issue: 3 Pages: 355-60
Publish Date 2015 Jul-Sep
PubMed ID 26229325
PMC ID 4518374

Venous thromboembolism (VTE) is a common cause of postoperative morbidity and mortality in cystectomy patients.The aim of this study is to identify variables associated with risk of developing deep venous thrombosis (DVT) or pulmonary embolism (PE) within 90 days after radical cystectomy (RC).Retrospective chart review of patients undergoing RC from 2004 to 2011 at the University of Wisconsin.Clinical variables collected for all RC patients. All patients received mechanical prophylaxis, and routine heparin prophylaxis began in 2010.Univariate and multivariate analyses were used to evaluate VTE association with known risk factors.A total of 241 patients were identified with median age of 67.1 (interquartile range: 57.8-74.3) years. Body mass index (BMI) was ≥30 in 36.8% of patients. Median blood loss was 950 (600-1500) mL and 157/241 (65.2%) patients received a blood transfusion.Patients with BMI ≥30 or nonurothelial cancer are at highest risk for postoperative VTE and should be considered for extended heparin prophylaxis.

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