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Tracy M Downs, MD, FACS

Contact Dr. Downs

E-mail:
downs@urology.wisc.edu

Phone:
(608) 263-9534

Mail:
UW Medical Foundation Centennial Building
1685 Highland Ave
Madison, WI 53705-2281

Tracy M Downs, MD, FACS

Professor (CHS)
Director, Bladder Cancer and Intravesical Therapy Programs

Education

  • MD, University of California-San Diego, La Jolla, CA, 1993
  • Internship, Brigham and Women’s Hospital (Harvard), Boston, MA, 1995
  • Clinical Nutrition Fellowship, Harvard, Boston, MA, 1999
  • Residency, Brigham and Women’s Hospital (Harvard), Boston, MA, 2001
  • Research Fellowship, University of California-San Francisco, San Francisco, CA, 2003
  • Urologic Oncology Fellowship, University of California-San Francisco, San Francisco, CA, 2003

Clinical Specialties

Dr. Downs is certified by the American Board of Urology. He specializes in the surgical treatment of urologic cancers and treats all forms of urologic cancers including bladder cancer, prostate cancer, kidney cancer, testis cancer and penile cancer. He has a special interest in the treatment of bladder cancer, where he performs robotic cystectomy (da Vinci robotic system), along with complex urinary reconstruction to make a new internalized bladder (orthotopic neobladder). Dr. Downs’ clinical care philosophy is to provide compassionate, cutting-edge urologic cancer care to his patients.

Research Interests

Dr. Downs has a joint appointment with the UW Carbone Cancer Center, and his clinical research emphasizes developing new therapies for genitourinary cancers.

Research Focus
Chemoprevention – Bladder cancer, prostate cancer
Screening Programs – Bladder cancer screening for high-risk subjects
Outcomes Research – Patient outcomes of treatments for non-muscle invasive (superficial) bladder cancer and radical cystectomy
Translational Research – Discovery of molecular and urinary biomarkers (bladder cancer)
Quality of Life Outcomes – Bladder cancer, prostate cancer

Recent Publications
  • Richards KA, Ruiz VL, Murphy DR, Downs TM, Abel EJ, Jarrard DF, Singh H. Diagnostic evaluation of patients presenting with hematuria: An electronic health record-based study. Urol. Oncol. 2018 Mar; 36(3):88.e19-88.e25.
    [PubMed ID: 29169843]
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  • Spiess PE, Agarwal N, Bangs R, Boorjian SA, Buyyounouski MK, Clark PE, Downs TM, Efstathiou JA, Flaig TW, Friedlander T, Greenberg RE, Guru KA, Hahn N, Herr HW, Hoimes C, Inman BA, Jimbo M, Kader AK, Lele SM, Meeks JJ, Michalski J, Montgomery JS, Pagliaro LC, Pal SK, Patterson A, Plimack ER, Pohar KS, Porter MP, Preston MA, Sexton WJ, Siefker-Radtke AO, Sonpavde G, Tward J, Wile G, Dwyer MA, Gurski LA. Bladder Cancer, Version 5.2017, NCCN Clinical Practice Guidelines in Oncology. J Natl Compr Canc Netw 2017 Oct; 15(10):1240-1267.
    [PubMed ID: 28982750]
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  • Shore ND, Boorjian SA, Canter DJ, Ogan K, Karsh LI, Downs TM, Gomella LG, Kamat AM, Lotan Y, Svatek RS, Bivalacqua TJ, Grubb RL, Krupski TL, Lerner SP, Woods ME, Inman BA, Milowsky MI, Boyd A, Treasure FP, Gregory G, Sawutz DG, Yla-Herttuala S, Parker NR, Dinney CPN. Intravesical rAd-IFNα/Syn3 for Patients With High-Grade, Bacillus Calmette-Guerin-Refractory or Relapsed Non-Muscle-Invasive Bladder Cancer: A Phase II Randomized Study. J. Clin. Oncol. 2017 Oct 20; 35(30):3410-3416.
    [PubMed ID: 28834453, PMCID: 5648171]
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  • Wang JH, Downs TM, Jason Abel E, Richards KA, Jarrard DF. Prostate Biopsy in Active Surveillance Protocols: Immediate Re-biopsy and Timing of Subsequent Biopsies. Curr Urol Rep 2017 Jul; 18(7):48.
    [PubMed ID: 28589399]
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  • Blute ML, Kucherov V, Rushmer TJ, Damodaran S, Shi F, Abel EJ, Jarrard DF, Richards KA, Messing EM, Downs TM. Reduced estimated glomerular filtration rate (eGFR <60 mL/min/1.73 m2 ) at first transurethral resection of bladder tumour is a significant predictor of subsequent recurrence and progression. BJU Int. 2017 09; 120(3):387-393.
    [PubMed ID: 28464520]
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  • Tazeh NN, Canter DJ, Damodaran S, Rushmer T, Richards KA, Abel EJ, Jarrard DF, Downs TM. Neutrophil to Lymphocyte Ratio (NLR) at the Time of Transurethral Resection of Bladder Tumor: A Large Retrospective Study and Analysis of Racial Differences. Bladder Cancer 2017 Apr 27; 3(2):89-94.
    [PubMed ID: 28516153, PMCID: 5409044]
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  • Ravvaz K, Walz ME, Weissert JA, Downs TM. Predicting Nonmuscle Invasive Bladder Cancer Recurrence and Progression in a United States Population. J. Urol. 2017 Oct; 198(4):824-831.
    [PubMed ID: 28433642]
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  • Tobert CM, Hamilton-Reeves JM, Norian LA, Hung C, Brooks NA, Holzbeierlein JM, Downs TM, Robertson DP, Grossman R, Nepple KG. Emerging Impact of Malnutrition on Surgical Patients: Literature Review and Potential Implications for Cystectomy in Bladder Cancer. J. Urol. 2017 Sep; 198(3):511-519.
    [PubMed ID: 28286066, PMCID: 5705177]
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  • Blute ML, Damaschke N, Wagner J, Yang B, Gleave M, Fazli L, Shi F, Abel EJ, Downs TM, Huang W, Jarrard DF. Persistence of senescent prostate cancer cells following prolonged neoadjuvant androgen deprivation therapy. PLoS ONE 2017; 12(2):e0172048.
    [PubMed ID: 28234906, PMCID: 5325224]
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  • Jay R, Heckman JE, Hinshaw L, Best S, Lubner M, Jarrard DF, Downs TM, Nakada SY, Lee FT, Huang W, Ziemlewicz T. Multi-quadrant biopsy technique improves diagnostic ability in large heterogeneous renal masses. Abel EJ, Heckman JE, Hinshaw L, Best S, Lubner M, Jarrard DF, Downs TM, Nakada SY, Lee FT Jr, Huang W, Ziemlewicz T.J Urol. 2015 Oct;194(4):886-91. [Epub 2015 Mar 30]. doi: 10.1016/j.juro.2015.03.106. Urol. Oncol. 2017 Mar; 35(3):119.
    [PubMed ID: 28159492]
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