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Dale E Bjorling, DVM

Contact Dr. Bjorling


(608) 263-4808

Department of Surgical Sciences
MADISON, WI 53706-1100

(608) 263-7930

Dale E Bjorling, DVM

O’Brien Center Co-Director
Professor of Surgical Sciences
Associate Dean of Research
School of Veterinary Medicine


  • Diplomate, American College of Veterinary Surgeons, 1985
  • MS, University of Georgia, 1982
  • Residency in Small Animal Surgery, University of Georgia, 1979-82
  • Internship in Small Animal Medicine and Surgery, University of California, 1978-79
  • DVM, University of Illinois, 1978
  • BS, University of Illinois, 1976

Clinical Specialties

General surgery: primarily the urinary tract, thorax, biliary tract.

Research Interests

Inflammation of the bladder due to non-infectious causes, and mechanisms that modulate pain sensation and bladder healing. The laboratory’s primary research emphasis is the causes and pathogenesis of non-infectious cystitis and and the effects of infectious cystitis on the afferent nervous system. Clinical disorders of particular relevance to models used in the laboratory include urinary tract infection, Interstitial Cystitis (IC) in women, and Feline Urologic Syndrome (FUS) in cats. The goalsof this research are to identify processes that promote inflammation, damage, and pain within the bladder and to investigate improved therapeutic modalities for treatment or prevention of symptoms assocated with cystitis.

Recent Publications
  • Ritter KE, Wang Z, Vezina CM, Bjorling DE, Southard-Smith EM. Serotonin Receptor 5-HT3A Affects Development of Bladder Innervation and Urinary Bladder Function. Front Neurosci 2017; 11():690.
    [PubMed ID: 29311772, PMCID: 5732969]
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  • Bedoya Nader G, Kellihan HB, Bjorling DE, McAnulty J. Pyloric obstruction secondary to epicardial pacemaker implantation: a case report. J Vet Cardiol 2017 Feb; 19(1):95-98.
    [PubMed ID: 27913077]
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  • Hao L, Greer T, Page D, Shi Y, Vezina CM, Macoska JA, Marker PC, Bjorling DE, Bushman W, Ricke WA, Li L. In-Depth Characterization and Validation of Human Urine Metabolomes Reveal Novel Metabolic Signatures of Lower Urinary Tract Symptoms. Sci Rep 2016 Aug 09; 6():30869.
    [PubMed ID: 27502322, PMCID: 4977550]
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  • Lamarre NS, Bjorling DE. Treatment of painful bladder syndrome/interstitial cystitis with botulinum toxin A: why isn't it effective in all patients? Transl Androl Urol 2015 Oct; 4(5):543-54.
    [PubMed ID: 26816853, PMCID: 4708559]
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  • Greer T, Hao L, Nechyporenko A, Lee S, Vezina CM, Ricke WA, Marker PC, Bjorling DE, Bushman W, Li L. Custom 4-Plex DiLeu Isobaric Labels Enable Relative Quantification of Urinary Proteins in Men with Lower Urinary Tract Symptoms (LUTS). PLoS ONE 2015; 10(8):e0135415.
    [PubMed ID: 26267142, PMCID: 4534462]
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  • Jones MR, Wang ZY, Bjorling DE. Intrathecal cannabinoid-1 receptor agonist prevents referred hyperalgesia in acute acrolein-induced cystitis in rats. Am J Clin Exp Urol 2015; 3(1):28-35.
    [PubMed ID: 26069885, PMCID: 4446380]
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  • Bjorling DE, Wang Z, Vezina CM, Ricke WA, Keil KP, Yu W, Guo L, Zeidel ML, Hill WG. Evaluation of voiding assays in mice: impact of genetic strains and sex. Am. J. Physiol. Renal Physiol. 2015 Jun 15; 308(12):F1369-78.
    [PubMed ID: 25904700, PMCID: 4469884]
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  • Keil KP, Abler LL, Altmann HM, Wang Z, Wang P, Ricke WA, Bjorling DE, Vezina CM. Impact of a folic acid-enriched diet on urinary tract function in mice treated with testosterone and estradiol. Am. J. Physiol. Renal Physiol. 2015 Jun 15; 308(12):F1431-43.
    [PubMed ID: 25855514, PMCID: 4469891]
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  • Wang ZY, Wang P, Bjorling DE. Activation of cannabinoid receptor 1 inhibits increased bladder activity induced by nerve growth factor. Neurosci. Lett. 2015 Mar 04; 589():19-24.
    [PubMed ID: 25575795, PMCID: 4339033]
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  • Keil KP, Abler LL, Altmann HM, Bushman W, Marker PC, Li L, Ricke WA, Bjorling DE, Vezina CM. Influence of animal husbandry practices on void spot assay outcomes in C57BL/6J male mice. Neurourol. Urodyn. 2016 Feb; 35(2):192-8.
    [PubMed ID: 25394276, PMCID: 4428995]
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